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Ashland 1,2-Hexanediol Multifunctional diol CAS No. [6920-22-5] Cosmetic grade Moisturizing preservative synergist

Ashland 1,2-Hexanediol Multifunctional diol CAS No. [6920-22-5] Cosmetic grade Moisturizing preservative synergist

Ashland 1,2-hexanediol is a C6 diol produced by biological fermentation, which has the triple functions of small molecule moisturizing, antiseptic enhancement and solvent. Its unique "four-carbon straight chain" structure brings better spreadability and antibacterial properties than pentanediol, making it an ideal active ingredient for "additive-free" cosmetics and medical dressings.

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EFFISIN HD Polyol 2-Hexanediol CAS No. 6920-22-5 C6 Diol Preservative-free Moisturizer Acne Product Enhancer Ashland 1 2-Hexanediol CAS 6920-22-5

PRODUCT CATEGORY

Cosmetic Raw Materials

Product Description

Advantage

Process

FAQ

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CAS number	6920-22-5
Appearance	Colorless transparent liquid
Purity (GC)	≥99.5%
Water content (KF)	≤0.2%
Viscosity (25°C, mPa·s)	20-25
Boiling point (°C)	S223-227
Flash point (closed cup, °C)	11500%
Heavy metal (Pb)	≤1ppm

Daily Chemical Industry:

Suitable for cosmetics, coatings and industrial cleaning agents

Product Advantage

1

Triple effect breakthrough

Long-lasting moisturizing: 8-hour transepidermal water loss (TEWL) is reduced by 35%
Broad-spectrum antibacterial: The MIC value for Propionibacterium acnes is only 0.8%
Enhancing penetration and enhancing efficacy: Increases the absorption rate of niacinamide by 50%

2

Safety certification

Passed the EU SCCS assessment (SCCS/1637/21)
Included in the 2023 edition of China's ""Catalogue of Used Cosmetic Ingredients""
Passed the EWG SkinDeep® Level 1 safety rating

3

Formula innovation 1

Replaces 40% of the traditional preservatives
Solve the sticky problem of polyols (viscosity is only 23mPa·s)

4

Formula innovation 2

Improve the stability of active ingredients (vitamin C half-life is extended by 2 times)

Operate Process

Skin care product applications:

Preservative-free system:

Add 6-10% + 0.5% octanediol

pH range 4.0-6.5 is optimal

Active essence:

Combined with niacinamide 4:1 (penetration rate ↑50%)

Avoid direct mixing with high concentration carbomer (＞1%)

Lyophilized preparations:

Replace 50% glycerol (freeze resistance up to -30℃)

Incompatible combinations:

❌ Esterification is easy in strong acidic environment (pH＜3)

❌ Possible flocculation with cationic polymers

FAQ

Q1: What is the difference with 1,2-pentanediol?

→ Antibacterial property: 2 times stronger against G-bacteria (Pseudomonas aeruginosa MIC 0.6% vs 1.2%)
→ Skin feel: 15% lower viscosity (23mPa·s vs 27mPa·s)
Q2: Will it irritate the eyes?

→ Eye irritation index of 3% solution is 0.3 (rabbit eye test), it is recommended that products around the eyes should be ≤2%
Q3: Can it be sterilized at high temperature?

→ Can withstand 121℃/20min (decomposition rate <1%)